Designer/illustrator Victor Melendez's work is a playful tribute to his Mexican heritage. I really like his charming lunchadores. Check out his design portfolio for some impressive stuff as well, and his toy for Speakerdog.
Aaron Blecha has a very fun site that is loaded with wacky illustrations of monsters, mad scientists and other minions. Check out his super animation reel for a glimpse of his critters in action!
Wisconsin-based Max Estes does brilliantly colored cartoons, and keeps a daily blog called My Life as a Bunny, which is full of interesting insights about the little things in life.
Jesse Willmon's cartoon illustrations are a perfect fit for humor, which is probably why me has Comedy Central as one of his clients. He's also just launched a new site for his illustrated greeting cards.
Illustrophile is a blog showcasing illustrators new and old, from around the world. It is run by Charlene Chua, herself an illustrator based in Toronto.
Please send site suggestions etc to illustrophile[AT]gmail.com, or use the form on the Contact page.